mutM, a second mutator locus in Escherichia coli that generates G.C----T.A transversions.
نویسندگان
چکیده
We used strains carrying specific lacZ alleles to identify a new mutator locus in Escherichia coli which generates only G.C----T.A transversions among base substitutions. The locus, mutM, mapped near the cysE locus, which is at 81 min on the genetic map.
منابع مشابه
The mutY gene: a mutator locus in Escherichia coli that generates G.C----T.A transversions.
We have used a strain with an altered lacZ gene, which reverts to wild type via only certain transversions, to detect transversion-specific mutators in Escherichia coli. Detection relied on a papillation technique that uses a combination of beta-galactosides to reveal blue Lac+ papillae. One class of mutators is specific for the G.C----T.A transversion as determined by the reversion pattern of ...
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ورودعنوان ژورنال:
- Journal of bacteriology
دوره 170 11 شماره
صفحات -
تاریخ انتشار 1988